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Pregnancy: There are no sufficient clinical data available to evaluate possible risks of the use of fentanyl during pregnancy. For this reason fentanyl should not be used in this period.
It is advised not to use fentanyl during delivery, because fentanyl passes the placenta and may cause respiratory depression in the neonate.
In obstetrics, fentanyl may only be used intravenously after clamping the umbilical cord. The placental transfer (fetal: maternal ratio) amounts to 0.44 (1.00 : 2.27).
Lactation: Fentanyl passes into breast milk. After the application of fentanyl, breast feeding should be stopped for at least 24 hours.
